Browsing Pathways
Showing 21 -
30 of 605359 pathways
SMPDB ID | Pathway Name and Description | Pathway Class | Chemical Compounds | Proteins |
---|---|---|---|---|
SMP0122741View Pathway |
chebulagic acid Metabolism 1559277983 1589861306 1597248631 |
Signaling
|
|
|
SMP0122721View Pathway |
chebulagic acid Metabolism 1559277983 1596798296 |
Signaling
|
|
|
SMP0122484View Pathway |
chebulagic acid Metabolism 1581167212 |
Signaling
|
|
|
SMP0122497View Pathway |
chebulagic acid Metabolism 1581839290 |
Signaling
|
|
|
SMP0122514View Pathway |
chebulagic acid Metabolism 1582757459 |
Signaling
|
||
SMP0122879View Pathway |
chebulagic acid Metabolism 1602639807 |
Physiological
|
|
|
SMP0122891View Pathway |
chebulagic acid Metabolism 1602980507 |
|
||
SMP0122893View Pathway |
chebulagic acid Metabolism 1602981862 |
|
||
SMP0126782View Pathway |
Dolasetron Serotonin antagonist Action PathwayDolasetron is a selective serotonin 5-HT3 receptor antagonist. In vivo, the drug is rapidly converted into its major active metabolite, hydrodolasetron, which seems to be largely responsible for the drug's pharmacological activity. The antiemetic activity of the drug is brought about through the inhibition of 5-HT3 receptors present both centrally (medullary chemoreceptor zone) and peripherally (GI tract). This inhibition of 5-HT3 receptors in turn inhibits the visceral afferent stimulation of the vomiting center, likely indirectly at the level of the area postrema, as well as through direct inhibition of serotonin activity within the area postrema and the chemoreceptor trigger zone.
|
Drug Action
|
||
SMP0126594View Pathway |
Donepezil Acetylcholinesterase Inhibitor Action PathwayDonepezil is an acetylcholinesterase inhibitor that is used in the treatment of Alzheimer's Disease and dementia. It is administered orally or transdermally, sometimes in combination with memantine in order to treat moderate to severe dementia. Donepezil selectively inhibits the acetylcholinesterase enzyme, by doing so it is believed to enhance cholinergic transmission to relieve the symptoms of Alzheimer and dementia.
|
Drug Action
|
|
Showing 21 -
30 of 127858 pathways