SMPDB

Showing 331 - 340 of 605359 pathways

SMPDB ID	Pathway Name and Description	Pathway Class	Chemical Compounds	Proteins
SMP0001882 View Pathway	EXAMPLE: Excitatory Neural Signalling Through 5-HTR 4 and Serotonin 1441179644 BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling	Adenosine triphosphate cAMP Guanosine diphosphate Guanosine triphosphate Magnesium Phosphate Pyrophosphate Serotonin ( show all show less )	5-hydroxytryptamine receptor 4 Adenylate cyclase type 2 cAMP-dependent protein kinase ... Cyclic AMP-responsive element-... Ethylene-responsive transcript... Guanine nucleotide-binding pro... Guanine nucleotide-binding pro... Gβ Serine/threonine-protein phosp... ( show all show less )
SMP0001880 View Pathway	EXAMPLE: Dopamine Activation of Neurological Reward System 1441179389 BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling	Adenosine triphosphate cAMP Dopamine Guanosine diphosphate Guanosine triphosphate Magnesium Pyrophosphate ( show all show less )	Adenylate cyclase type 2 cAMP-dependent protein kinase ... D(1A) dopamine receptor Guanine nucleotide-binding pro... Guanine nucleotide-binding pro... Gβ ( show all show less )
SMP0001879 View Pathway	Alanine 1441179314 BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling	1-Methylhistidine	5'-nucleotidase
SMP0001812 View Pathway	Alanine BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling	1-Methylhistidine 2,4-Toluenediamine Aspirin Heme	5'-nucleotidase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2
SMP0001012 View Pathway	Test Testing Pathwhiz BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling		Cellular tumor antigen p53
SMP0001011 View Pathway	Test Pathwas Testing PathWhiz BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling		C-X-C chemokine receptor type ... UMP-CMP kinase
SMP0000978 View Pathway	tut1 tut1 tpd52 BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling		5'-nucleotidase
SMP0000862 View Pathway	Wnt BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling
SMP0000772 View Pathway	EXAMPLE: Intracellular Signalling Through PGD2 receptor and Prostaglandin D2 PGD is the major prostanoid released from human mast cells upon immunological challenge. Knockout studies in mice suggest that prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. The PGD receptor activates G(s) proteins which lead to the activation of adenylyl cyclase which produces the secondary messenger cAMP. cAMP activates PKA (protein kinase A) which phosphorylates downstream effectors that lead to a specific cellular response. BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling	Adenosine triphosphate cAMP Guanosine diphosphate Guanosine triphosphate Magnesium Prostaglandin D2 Pyrophosphate ( show all show less )	Adenylate cyclase type 2 cAMP-dependent protein kinase ... Guanine nucleotide-binding pro... Guanine nucleotide-binding pro... Gβ Prostaglandin D2 receptor ( show all show less )
SMP0000771 View Pathway	EXAMPLE: Intracellular Signalling Through Histamine H2 Receptor and Histamine Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. The H2 receptor activates G(s) proteins which lead to the activation of adenylyl cyclase which produces the secondary messenger cAMP. cAMP activates PKA (protein kinase A) which phosphorylates downstream effectors that lead to a specific cellular response. BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling	Adenosine triphosphate cAMP Guanosine diphosphate Guanosine triphosphate Histamine Magnesium Phosphate Pyrophosphate ( show all show less )	Adenylate cyclase type 2 cAMP-dependent protein kinase ... Cyclic AMP-responsive element-... Ethylene-responsive transcript... Guanine nucleotide-binding pro... Guanine nucleotide-binding pro... Gβ Histamine H2 receptor Serine/threonine-protein phosp... ( show all show less )