PathWhiz ID | Pathway | Meta Data |
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PW145668View Pathway |
drug action
Noscapine Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 16:20 Last Updated: October 07, 2023 at 16:20 |
PW064693View Pathway |
signaling
NotchHomo sapiens
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Creator: Guest: Anonymous Created On: February 28, 2018 at 09:34 Last Updated: February 28, 2018 at 09:34 |
PW124223View Pathway |
signaling
Notch signalling pathwayHomo sapiens
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Creator: Guest: Anonymous Created On: October 14, 2020 at 02:59 Last Updated: October 14, 2020 at 02:59 |
PW064734View Pathway |
signaling
notch1Homo sapiens
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Creator: Guest: Anonymous Created On: May 10, 2018 at 01:17 Last Updated: May 10, 2018 at 01:17 |
PW145145View Pathway |
drug action
Novobiocin Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 15:10 Last Updated: October 07, 2023 at 15:10 |
PW176424View Pathway |
Novobiocin Predicted Metabolism PathwayHomo sapiens
Metabolites of Novobiocin are predicted with biotransformer.
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Creator: Omolola Created On: December 08, 2023 at 13:51 Last Updated: December 08, 2023 at 13:51 |
PW132287View Pathway |
Noxytiolin Drug MetabolismHomo sapiens
Noxytiolin is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Noxytiolin passes through the liver and is then excreted from the body mainly through the kidney.
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Creator: Ray Kruger Created On: September 21, 2023 at 20:38 Last Updated: September 21, 2023 at 20:38 |
PW146682View Pathway |
drug action
Noxytiolin Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 18:47 Last Updated: October 07, 2023 at 18:47 |
PW122236View Pathway |
signaling
npr 1-1Arabidopsis thaliana
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Creator: Guest: Anonymous Created On: September 21, 2018 at 05:28 Last Updated: September 21, 2018 at 05:28 |
PW124178View Pathway |
signaling
Nuclear factor kappa-B (NF-κB) PathwayHomo sapiens
NF-kB protein dimmers as nuclear transcription factor, they need to migrate to the nucleus, combined with DNA to have function. In most types of the normal cells under resting state, NF-KB was inactive and retain in the cytoplasm. They binding to a specific inhibitors called IK-B protein, which could bind to the Rel homology domain (RHD) of NF-kB and interfere with its nuclear localization sequence (NLS) function. These inhibitor proteins, which include IkBa, IkBb and IkBg, contain 6–7 ankyrin repeats that mediate binding to the RHD. These repeats are also present in the C-terminal halves of the NF-kB2/p100 and NF-kB1/p105 precursors, which also function as IkBs and retain their partners, the Rel proteins, in the cytoplasm. In order to activate the NF-kB molecular, the cells first need to separate the NF-kB protein from their inhibitors. There are two major signaling pathways lead to the IK-B protein inhibitor dissociation from NF-kB dimmer and let the translocation of NF-kB dimers from the cytoplasm into the nucleus.
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Creator: Guest: Anonymous Created On: September 25, 2020 at 06:45 Last Updated: September 25, 2020 at 06:45 |