SMPDB

Showing 71 - 80 of 605359 pathways

SMPDB ID	Pathway Name and Description	Pathway Class	Chemical Compounds	Proteins
SMP0125310 View Pathway	PIP3 to PIP2 signaling on plasma membrane BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling	L-Cystine	Phosphatidylinositol 3-kinase ... Phosphatidylinositol 3-kinase ... Phosphatidylinositol 3-kinase ...
SMP0125305 View Pathway	Mitocondria BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling	1-Methylhistidine Calcium	5'-nucleotidase
SMP0125298 View Pathway	Proliferation BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling		Dickkopf-related protein 1 Frizzled-1 Frizzled-10 Frizzled-2 Frizzled-3 Frizzled-4 Frizzled-5 Frizzled-6 Frizzled-7 Frizzled-8 Frizzled-9 Proto-oncogene Wnt-1 Wnt inhibitory factor 1 ( show all show less )
SMP0125295 View Pathway	Muscle Atrophy 2 BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling
SMP0125284 View Pathway	apoptosis--- 1649492111 BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling
SMP0125280 View Pathway	mTOR lipogenesis BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling	Insulin	Phosphatidylinositol-4,5-bisph...
SMP0125278 View Pathway	Mypathway 1649232916 BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling	2,4-Toluenediamine	5'-nucleotidase
SMP0125273 View Pathway	PI3-Akt signalling pathway leading apoptosis Amoxicillin and clavulanic acid induced apoptosis BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling	Phosphate	14-3-3 protein eta 3-phosphoinositide-dependent p... Bcl2-associated agonist of cel... Caspase-9 Caspase-9 Forkhead box protein O1 Forkhead box protein O3 Forkhead box protein O4 Growth hormone receptor Heat shock protein HSP 90-alph... Inhibitor of nuclear factor ka... Inhibitor of nuclear factor ka... NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105... Phosphatidylinositol 3-kinase ... Phosphatidylinositol-4,5-bisph... Phosphatidylinositol-4,5-bisph... RAC-alpha serine/threonine-pro... Serine/threonine-protein phosp... Somatotropin Transcription factor p65 Tumor necrosis factor ligand s... ( show all show less )
SMP0125254 View Pathway	Intestinal Serotonin pathway More than 90% of serotonin or 5-hydroxytryptamine is produced and found in the gut. Serotonin activates alpha adrenergic receptors which activates the Gq protein cascade. This activates Phospolipase C which catalyzes Phosphatidylinositol 4,5-bisphosphate into Inositol 1,4,5-trisphosphate and Diacylglycerol. Diacylglycerol activates protain kinase C which activates the voltage-dependent calcium channel, allowing calcium to enter the cell. Inositol 1,4,5-trisphosphate activates Inositol 1,4,5-trisphosphate receptor on the sarcoplasmic reticulum which also allows calcium to enter the cell from the sarcoplasmic reticulum. This high concentration of calcium in the cytosol attaches to calmodulin which activates Myosin light chain kinase. This enzyme catalyzes Myosin light chain 3 into myosin LC-P which causes myosin to bind to actin and contract the muscle cell. The contraction of this smooth muscle causes the blood vessel to constrict. This causes the intestine to contract more often which causes food to move through more quickly. The faster the food moves through the intestine, the less nutrients are absorbed from the food into blood vessels. BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling	Calcium Inositol 1,4,5-trisphosphate Magnesium Manganese Phosphatidylinositol 4,5-bisphosphate Serotonin ( show all show less )	1-phosphatidylinositol 4,5-bis... 5-hydroxytryptamine receptor 2... Calmodulin-1 Guanine nucleotide-binding pro... Inositol 1,4,5-trisphosphate r... Myosin light chain 3 Myosin light chain kinase, smo... Protein kinase C alpha type Serine/threonine-protein phosp... Voltage-dependent calcium chan... Voltage-dependent L-type calci... Voltage-dependent P/Q-type cal... ( show all show less )
SMP0125185 View Pathway	apoptosis--- BioPAX SVG SBGN SBML PWML All files (.zip)	Signaling

Showing 71 - 80 of 350 pathways