Release 1.0 - January 1, 2009

• Initial SMPDB release.

Release 2.0 - September 15, 2013

• Total number of pathways increased to more than 600.
• All 1.0 pathways are redrawn. Corrections have been made to dozens of them and many missing transporters have been added.
• All pathways now have a standarded appearance.
• Additional molecular and cellular information has been added to the pathways.
• Significant improvements have been made to SMPDB's visualization interface. Browsing, selection, re-coloring and zooming of pathways are now far easier and intuitive.
• A new pathway drawing tool called PathWhiz is integrated to the UI. SMPDB pathways can now be much more easily drawn and far more rapidly updated.
• Pathways made using PathWhiz can now be saved in BioPAX format.

February 19, 2015

• Total number of pathways increased to more than 700.
• Pathways can now be downloaded in SBML and SBGN format.
• PathWhiz is now available for public use.

Release SMPDB 2.75 - August 15, 2018

• All non-human pathways are now hosted on PathBank