SMPDB

Search for 'fentanyl' in 'all pathways' in 'Homo sapiens' returned 14 results

SMP0125203 View Pathway	Drug Action Fentanyl Opioid Agonist Action Pathway Matched Description: Fentanyl is a potent opioid agonistused for strong and rapid analgesia. It is used to treat strong … . Fentanyl can cross the blood-brain barrier where it binds to mu-type opioid receptors. The mu-type … opioid receptor is coupled with G-protein receptors. Binding of fentanyl stimulates the exchange of Matched Compounds: Fentanyl Matched Compound Synonyms: Fentanyl citrate … Fentanyl citrate … Fentanyl citrate BioPAX SVG SBGN SBML PWML All files (.zip)
SMP0125222 View Pathway	Metabolic Fentanyl Metabolism Matched Description: Fentanyl is an opioid that is injected intravenously or intramuscularly where it travels through … the blood to the liver. Fentanyl is 80-85% bound to plasma proteins. It is transported into the liver … via P-glycoprotein. In the endoplasmic reticulum of a hepatocyte in the liver, 99% of fentanyl is … metabolized into norfentanyl via the enzyme Cytochrome P450 3A4. Fentanyl is also predicted by … excreted as unchanged fentanyl in the urine while >1% is unchanged in the feces. Matched Compounds: Fentanyl Matched Compound Synonyms: Fentanyl citrate … Fentanyl citrate BioPAX SVG SBGN SBML PWML All files (.zip)
SMP0143252 View Pathway	Drug Action Fentanyl Drug Metabolism Action Pathway Matched Compounds: Fentanyl Matched Compound Synonyms: Fentanyl citrate … Fentanyl citrate BioPAX SVG SBGN SBML PWML All files (.zip)
SMP0000415 View Pathway	Drug Action Fentanyl Action Pathway Matched Compounds: Fentanyl Matched Compound Synonyms: Fentanyl citrate BioPAX SVG SBGN SBML PWML All files (.zip)
SMP0000417 View Pathway	Drug Action Sufentanil Action Pathway Matched Description: Sufentanil is a pharmacologically-active synthetic small molecule derived from fentanyl and belongs BioPAX SVG SBGN SBML PWML All files (.zip)
SMP0000416 View Pathway	Drug Action Remifentanil Action Pathway Matched Description: Remifentanil is a pharmacologically-active, synthetic, small molecule derived from fentanyl and BioPAX SVG SBGN SBML PWML All files (.zip)
SMP0125517 View Pathway	Metabolic Alfentanil Metabolism Pathway Matched Description: short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic BioPAX SVG SBGN SBML PWML All files (.zip)
SMP0126798 View Pathway	Drug Action Lofentanil Opioid Agonist Action Pathway Matched Description: Lofentanil is an analog of fentanyl and a potent opioid. Lofentanil binds to opioid receptors BioPAX SVG SBGN SBML PWML All files (.zip)
SMP0125012 View Pathway	Drug Action 3-Methylthiofentanyl Opioid Agonist Action Pathway Matched Description: 3-Methyl-thiofentanyl is a fentanyl analog and an opioid analgesic that works by inducing central BioPAX SVG SBGN SBML PWML All files (.zip)
SMP0125010 View Pathway	Drug Action Carfentanil Opioid Agonist Action Pathway Matched Description: Carfentanil is an analogue of the popular synthetic opioid analgesic fentanyl, and is one of the BioPAX SVG SBGN SBML PWML All files (.zip)