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Tryptophan
2,3-dioxygenase
Kynureninase
Kynurenine
formamidase
Kynurenine
formamidase
Kynureninase
Kynurenine/alpha-
aminoadipate
aminotransferase,
mitochondrial
Kynurenine
3-monooxygenase
Kynureninase
Catalase
Kynurenine/alpha-
aminoadipate
aminotransferase,
mitochondrial
3-
hydroxyanthranilate
3,4-dioxygenase
2-amino-3-
carboxymuconate-
6-semialdehyde
decarboxylase
Tryptophan
5-hydroxylase 1
Aromatic-L-
amino-acid
decarboxylase
Kynurenine
3-monooxygenase
Aldehyde
dehydrogenase,
mitochondrial
Acetylserotonin
O-
methyltransferase
Kynurenine
formamidase
Indoleamine
2,3-dioxygenase 1
Aromatic-L-
amino-acid
decarboxylase
Kynurenine
3-monooxygenase
Serotonin N-
acetyltransferase
Acetylserotonin
O-
methyltransferase
Cytochrome P450
1A1
Indoleamine
2,3-dioxygenase 1
Indolethylamine
N-
methyltransferase
Indoleamine
2,3-dioxygenase 1
Aromatic-L-
amino-acid
decarboxylase
Kynurenine
3-monooxygenase
Aldehyde
dehydrogenase,
mitochondrial
Indolethylamine
N-
methyltransferase
Aldehyde oxidase
Indoleamine
2,3-dioxygenase 1
Tryptophan--tRNA
ligase,
cytoplasmic
Tryptophan--tRNA
ligase,
mitochondrial
Quinolinic acid
L-Tryptophan
L-Tryptophan
O
2
N'-
Formylkynurenine
H
2
O
Formylanthranilic
acid
L-Alanine
H
2
O
L-Kynurenine
Formic acid
H
2
O
2-Aminobenzoic
acid
Formic acid
H
2
O
L-Alanine
4-(2-
Aminophenyl)-
2,4-
dioxobutanoic
acid
Kynurenic acid
Oxoglutaric acid
L-Glutamic acid
NADPH
O
2
L-3-
Hydroxykynurenine
NADP
H
2
O
H
2
O