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Pathway Description
Azithromycin Action Pathway
Homo sapiens
Drug Action Pathway
Created: 2013-08-22
Last Updated: 2025-01-29
Azithromycin, trade names include Zithromax and Azithrocin, is a semisynthetic azalide derived from erythromycin. Azalides are part of the macrolide antibiotic class. Azithromycin targets protein synthesis of bacteria by binding to the 50S subunit of the bacterial ribosome to inhibit mRNA translation and prevent bacteria growth. Macrolides are broad spectrum antibiotics. It is prescribed to treat bacterial infections including: sexually transmitted infections like chlamydia, pneumonia, strep throat, ear infections, sinusitis and more.
References
Azithromycin Pathway References
Song, K.S. Ribosomal protein synthesis inhibitors. In S. Offermanns, & W. Rosenthal (Eds.). Encyclopedic reference of molecular pharmacology. (2004) p. 827-833. Berlin, Germany: Springer.
Zithromax. (2009). e-CPS (online version of Compendium of Pharmaceuticals and Specialties). Retrieved July 17, 2009.
Bakheit AH, Al-Hadiya BM, Abd-Elgalil AA: Azithromycin. Profiles Drug Subst Excip Relat Methodol. 2014;39:1-40. doi: 10.1016/B978-0-12-800173-8.00001-5.
Pubmed: 24794904
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