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Feline leukemia
virus subgroup
C receptor-
related protein
2
5-
aminolevulinate
synthase,
nonspecific,
mitochondrial
Delta-
aminolevulinic
acid
dehydratase
Porphobilinogen
deaminase
Uroporphyrinogen-
III synthase
Uroporphyrinogen
decarboxylase
Uroporphyrinogen
decarboxylase
Coproporphyrinogen-
III oxidase,
mitochondrial
Ferritin,
mitochondrial
Ferrochelatase,
mitochondrial
Protoheme IX
farnesyltransferase,
mitochondrial
Cytochrome c
oxidase
assembly
protein COX15
homolog
Biliverdin
reductase A
UDP-
glucuronosyltransferase
2B11
Beta-
glucuronidase
Protoporphyrinogen
oxidase
Heme oxygenase
1
Glycine
Coproporphyrinogen III
Coproporphyrinogen III
Protoporphyrin IX
Protoporphyrin IX
Heme
Heme
Succinyl-CoA
Accumulation
5-Aminolevulinic acid
CO
2
Accumulation
Porphobilinogen
H
2
O
H
2
O
Hydroxymethylbilane
NH
3
Uroporphyrinogen III
H
2
O
Uroporphyrin III
Uroporphyrinogen I
Coproporphyrinogen I
CO
2
Coproporphyrin I
Uroporphyrin I
CO
2
Coproporphyrin III
O
2
H
+
Protoporphyrinogen IX
CO
2
H
2
O
Fe2+
H
+
O
2
Fe3+
H
2
O
H
+
Farnesyl pyrophosphate
Heme O
Heme A
Biliverdin
NAD
Bilirubin
NADH
Uridine diphosphate glucuronic
acid
Bilirubin diglucuronide
Uridine 5'-diphosphate
H
2
O
Urobilinogen
O
2