Quantitative metabolomics services for biomarker discovery and validation.
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Cytochrome P450 2C8 Cytochrome P450 2C9 Cytochrome P450 2B6 Cytochrome P450 3A4 Cytochrome P450 3A5 Cytochrome P450 2A6 Retinal dehydrogenase 1 Aldehyde dehydrogenase, dimeric NADP-preferring Retinal dehydrogenase 1 Cytochrome P450 3A4 Cytochrome P450 3A5 Cytochrome P450 2B6 Aldoifosfamide 4-Hydroxyifosfamide Aldoifosfamide Acrolein Alcoifosfamide Isophosphamide mustard Ifosforamide Aziridinium Cl- 4-Ketoifosfamide Ifosfamide O2 NADPH H+ H2O NADP NAD H2O Acrylic acid NADH H+ H2O NAD Carboxyifosfamide NADH H+ O2 H2O Chloroacetaldehyde 3-Dechloroethylifosfamide 2-Dechloroethylifosfamide H2O2 Heme Heme Heme Heme Heme Heme Heme Heme Heme Endoplasmic Reticulum Membrane
Endoplasmic Reticulum CYP2C8 CYP2C9 CYP2B6 CYP3A4 CYP3A5 CYP2A6 ALDH1A1 ALDH3A1 ALDH1A1 CYP3A4 CYP3A5 CYP2B6 Aldoifosfamide 4- Hydroxyifosfamide Aldoifosfamide Acrolein Alcoifosfamide Isophosphamide mustard Ifosforamide Aziridinium Chloride ion 4- Ketoifosfamide Ifosfamide Oxygen NADPH Hydrogen Ion Water NADP NAD Water Acrylic acid NADH Hydrogen Ion Water NAD Carboxyifosfamide NADH Hydrogen Ion Oxygen Water Chloroacetaldehyde 3- Dechloroethylifosfamide 2- Dechloroethylifosfamide Hydrogen peroxide
CYP2C8 CYP2C9 CYP2B6 CYP3A4 CYP3A5 CYP2A6 ALDH1A1 ALDH3A1 ALDH1A1 CYP3A4 CYP3A5 CYP2B6 Aldifo 4Hiff Aldifo Acrolen Alcifo Isophos IFFAzm Cl- 4kffm Ifosfam O2 NADPH H+ H2O NADP NAD H2O AcryliA NADH H+ H2O NAD Caroxyf NADH H+ O2 H2O chlogl 3DCLFA 2Dcel H2O2 Heme Heme Heme Heme Heme Heme Heme Heme Heme Endoplasmic Reticulum Membrane
Endoplasmic Reticulum CYP2C8 CYP2C9 CYP2B6 CYP3A4 CYP3A5 CYP2A6 ALDH1A1 ALDH3A1 ALDH1A1 CYP3A4 CYP3A5 CYP2B6 Aldifo 4Hiff Aldifo Acrolen Alcifo Isophos IFFAzm Cl 4kffm Ifosfam O2 NADPH H+ H2O NADP NAD H2O AcryliA NADH H+ H2O NAD Caroxyf NADH H+ O2 H2O chlogl 3DCLFA 2Dcel H2O2