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Alcohol
dehydrogenase
1B
Aldehyde
dehydrogenase,
mitochondrial
Aldehyde
dehydrogenase
X,
mitochondrial
Cytochrome P450
2E1
Aldehyde
dehydrogenase,
mitochondrial
Catalase
Aldehyde
dehydrogenase,
mitochondrial
Acetyl-coenzyme
A synthetase,
cytoplasmic
Acetyl-coenzyme
A synthetase
2-like,
mitochondrial
Acetaldehyde
Acetaldehyde
Ethanol
Ethanol
Acetic acid
Acetic acid
Acetic acid
Acetic acid
Ethanol
NAD
Acetaldehyde
NADH
H
+
NAD
H
2
O
NADH
H
+
O
2
NADPH
H
2
O
NADP
NAD
H
2
O
NADH
H
+
Ethanol
H
2
O
2
Acetaldehyde
H
2
O
NAD
H
2
O
NADH
H
+
ATP
CoA
AMP
PP
i
Acetyl-CoA
ATP
CoA
AMP
PP
i
Zinc (II) ion
Heme
NADP
Heme
Extra Hepatic Cell
Hepatic Cell (I)
Hepatic Cell (II)
Hepatic Cell (III)
Endoplasmic Reticulum
Peroxisome
Mitochondria
Mitochondria
Cytoplasm
Liver
Endoplasmic Reticulum
ADH1B
ALDH2
ALDH1B1
CYP2E1
ALDH2
CAT
ALDH2
ACSS2
ACSS1
Acetaldehyde
Acetaldehyde
Ethanol
Ethanol
Acetic acid
Acetic acid
Acetic acid
Acetic acid
Ethanol
NAD
Acetaldehyde
NADH
Hydrogen Ion
NAD
Water
NADH
Hydrogen Ion
Oxygen
NADPH
Water
NADP
NAD
Water
NADH
Hydrogen Ion
Ethanol
Hydrogen
peroxide
Acetaldehyde
Water
NAD
Water
NADH
Hydrogen Ion
Adenosine
triphosphate
Coenzyme A
Adenosine
monophosphate
Pyrophosphate
Acetyl-CoA
Adenosine
triphosphate
Coenzyme A
Adenosine
monophosphate
Pyrophosphate