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Ras-related C3
botulinum toxin
substrate 1
Amidophosphoribosyltransferase
Equilibrative
nucleoside
transporter 2
Solute carrier
family 28
member 3
Equilibrative
nucleoside
transporter 1
Sodium/nucleoside
cotransporter 2
Hypoxanthine-
guanine
phosphoribosyltransferase
Inosine-5'-
monophosphate
dehydrogenase 1
GMP synthase
[glutamine-
hydrolyzing]
Thiopurine S-
methyltransferase
Aldehyde
oxidase
Thiopurine S-
methyltransferase
Thiopurine S-
methyltransferase
Xanthine
dehydrogenase/oxidase
Adenosine
kinase
Thiopurine S-
methyltransferase
Multidrug
resistance-
associated
protein 5
Multidrug
resistance-
associated
protein 4
Multidrug
resistance-
associated
protein 5
Multidrug
resistance-
associated
protein 4
Multidrug
resistance-
associated
protein 4
Multidrug
resistance-
associated
protein 5
Mercaptopurine
Na
+
Na
+
Na
+
Na
+
Na
+
Na
+
Mercaptopurine
Phosphoribosyl pyrophosphate
6-Thioinosine-5'-monophosphate
NAD
H
2
O
Thioxanthine monophosphate
NADH
L-Glutamine
H
2
O
ATP
6-Thioguanosine monophosphate
AMP
PP
i
S-Adenosylmethionine
Methyl-thioguanosine
monophosphate
S-Adenosylhomocysteine
Thioguanosine 5'-diphosphate
1-phosphatidyl-1D-myo-inositol
4-phosphate
Thiodeoxyguanosine
5'-diphosphate
Thioguanosine 5'-triphosphate
8-Hydroxythioguanine
S-Adenosylmethionine
S-Adenosylhomocysteine
6-Methylmercaptopurine
6-Mercaptopurine riboside
S-Adenosylmethionine
S-Adenosylhomocysteine
NAD
H
2
O
6-thiouric acid
NADH
6-Methylthiopurine
5'-monophosphate
ribonucleotide
ATP
6-methylmercaptopurine
riboside
ADP
S-Adenosylmethionine
S-Adenosylhomocysteine
ATP
H
2
O
6-Thioguanosine monophosphate
ADP
P
i
ATP
H
2
O
ADP
P
i
ATP
H
2
O
6-Thioinosine-5'-monophosphate
ADP
P
i
ATP
H
2
O
ADP
P
i
ATP
H
2
O
Thioxanthine monophosphate
ADP
P
i
ATP
H
2
O
ADP
P
i
Magnesium
Magnesium
Potassium
FAD
Molybdopterin
FAD
2Fe-2S
Molybdopterin