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Solute carrier
family 22
member 1
Solute carrier
family 22
member 2
Solute carrier
family 22
member 3
Multidrug
resistance-
associated
protein 1
Canalicular
multispecific
organic anion
transporter 1
Canalicular
multispecific
organic anion
transporter 2
Multidrug
resistance
protein 1
Multidrug
resistance-
associated
protein 4
ATP-binding
cassette
sub-family G
member 2
5'(3')-
deoxyribonucleotidase,
cytosolic type
Sulfotransferase
1A1
UMP-CMP kinase
Phosphoglycerate
kinase 1
Nucleoside
diphosphate
kinase A
Ethanolamine-
phosphate
cytidylyltransferase
Deoxycytidine
kinase
Cholinephosphotransferase
1
Choline-phosphate
cytidylyltransferase
A
Lamivudine
Lamivudine
Lamivudine
Lamivudine-
monophosphate
Lamivudine-
triphosphate
Lamivudine-
diphosphate
Lamivudine-
monophosphate
Lamivudine-
diphosphate-
ethanolamine
Uridine
5'-diphosphate
Uridine
triphosphate
H
2
O
O
2
Lamivudine
sulfoxide
H
2
O
2
ATP
ADP
ATP
ADP
O-
Phosphoethanolamine
Pyrophosphate
ATP
ADP
Lamivudine-
diphosphate-
choline
1,2-
diacylglycerol
Phosphorylcholine
Pyrophosphate
H
2
O
ATP
P
i
ADP
H
2
O
ATP
P
i
ADP
H
2
O
ATP
P
i
ADP
H
2
O
ATP
P
i
ADP
H
2
O
ATP
P
i
ADP
H
2
O
ATP
P
i
ADP
Magnesium
Magnesium
Magnesium
Magnesium
Phosphatidylcholine
HIV Reverse
Transcriptase
Nucleus
SLC22A1
SLC22A2
SLC22A3
ABCC1
ABCC2
ABCC3
ABCB1
ABCC4
ABCG2
NT5C
SULT1A1
CMPK1
PGK1
NME1
PCYT2
DCK
CHPT1
PCYT1A
Lamivudine
Lamivudine
Lamivudine
Lamivudine-
monophosphate
Lamivudine-
triphosphate
Lamivudine-
diphosphate
Lamivudine-
monophosphate
Lamivudine-
diphosphate-
ethanolamine
Uridine
5'-diphosphate
Uridine
triphosphate
Water
Oxygen
Lamivudine
sulfoxide
Hydrogen peroxide
Adenosine
triphosphate
Adenosine
diphosphate
Adenosine
triphosphate
Adenosine
diphosphate
O-
Phosphoethanolamine
Pyrophosphate
Adenosine
triphosphate
Adenosine
diphosphate
Lamivudine-
diphosphate-
choline
1,2-
diacylglycerol
Phosphorylcholine
Pyrophosphate
Water
Adenosine
triphosphate
Phosphate
Adenosine
diphosphate
Water
Adenosine
triphosphate
Phosphate
Adenosine
diphosphate
Water
Adenosine
triphosphate
Phosphate
Adenosine
diphosphate
Water
Adenosine
triphosphate
Phosphate
Adenosine
diphosphate
Water
Adenosine
triphosphate
Phosphate
Adenosine
diphosphate
Water
Adenosine
triphosphate
Phosphate
Adenosine
diphosphate
Phosphatidylcholine
HIV Reverse
Transcriptase