Lincomycin is a lincosamid antibiotic that can effectively aganist aerobic gram-positive cocci, aerobic gram-positive bacilli as well as anaerobic gram-positive sporeforming bacilli in vitro. Lincomycin is derived from yeast Streptomyces lincolnensis. Lincomycin can bind and inhibit 50S subunits of bacterial ribosomes to prevent protein synthesis, which result in cell death.
References
Lincomycin Pathway References
Spizek J, Rezanka T: Lincomycin, clindamycin and their applications. Appl Microbiol Biotechnol. 2004 May;64(4):455-64. doi: 10.1007/s00253-003-1545-7. Epub 2004 Feb 5.
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