SMPDB

Pathway Description

Delavirdine Action Pathway

Homo sapiens

Drug Action Pathway

Created: 2014-06-23

Last Updated: 2019-08-16

Delavirdine (also known as Rescriptor) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that can be used for treating HIV-1. Delavirdine can bind and inhibit the reverse transcriptase so that the DNA polymerase activities can be prevented, which lead to disruption of the enzyme's catalytic site and eventually lead to prevention of cell growth.

References

Delavirdine Pathway References

Freimuth WW: Delavirdine mesylate, a potent non-nucleoside HIV-1 reverse transcriptase inhibitor. Adv Exp Med Biol. 1996;394:279-89.

Pubmed: 8815692

Viral Transcription Inhibition References

Highlighted elements will appear in red.

Highlight Compounds

	Adenosine monophosphate
	Adenosine triphosphate
	Delavirdine
	Pyrophosphate

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