Rilpivirine, sold as Edurant, is an antiretroviral drug that works as a non-nucleoside reverse transcriptase inhibitor (NNRTI) to treat HIV infections. NNRTI drugs work by entering the cell that HIV is present in, and binding to HIV's reverse transcriptase protein. This inactivates it, preventing HIV from being able to produce cDNA from its RNA genome, effectively stopping it from replicating its genome and spreading. While NNRTIs are able to prevent HIV from replicating, it does not destroy the virus, and it is only useful to help slow down the progression of the disease, not curing it.

Rilpivirine Pathway References

Viral Transcription Inhibition References