Toggle navigation
SMPDB
Browse SMPDB
Pathways
Table of Primary Pathways
Compounds
Proteins
Search
TextQuery Search Instructions
SMP-MAP Advanced Search
ChemQuery Structure Search
Molecular Weight Search
Sequence Search
About
About SMPDB
Release Notes
Citing SMPDB
Statistics
Other Databases
Pathway Legend
Pathway Category Definitions
PathWhiz
Downloads
Contact Us
Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
Loading Pathway...
Error: Pathway image not found.
Malate
dehydrogenase,
mitochondrial
Lysine-specific
demethylase 2A
Hypoxia-
inducible
factor 1-alpha
Mitochondrial
pyruvate
carrier 1
Mitochondrial
dicarboxylate
carrier
Mitochondrial
citrate
transport
protein
Pyruvate
dehydrogenase
complex
Citrate
synthase,
mitochondrial
Isocitrate
dehydrogenase
[NAD] subunit
alpha,
mitochondrial
Isocitrate
dehydrogenase
[NAD] subunit
beta,
mitochondrial
Isocitrate
dehydrogenase
[NAD] subunit
gamma,
mitochondrial
Oxoglutarate
dehydrogenase
complex
Succinyl-CoA
ligase
Pyruvate
carboxylase,
mitochondrial
Aconitate
hydratase,
mitochondrial
Aconitate
hydratase,
mitochondrial
Isocitrate
dehydrogenase
[NADP]
cytoplasmic
NADP+-specific
isocitrate
dehydrogenase
Isocitrate
dehydrogenase
[NADP],
mitochondrial
Succinate
dehydrogenase
[ubiquinone]
flavoprotein
subunit,
mitochondrial
Succinate
dehydrogenase
[ubiquinone]
iron-sulfur
subunit,
mitochondrial
Succinate
dehydrogenase
cytochrome b560
subunit,
mitochondrial
Succinate
dehydrogenase
[ubiquinone]
cytochrome b
small subunit,
mitochondrial
Fumarate
hydratase,
mitochondrial
Egl nine
homolog 1
Egl nine
homolog 2
Egl nine
homolog 3
L-2-
hydroxyglutarate
dehydrogenase,
mitochondrial
Methylcytosine
dioxygenase
TET1
Pyruvic acid
FADH
2
Pyruvic acid
Fumaric acid
Citric acid
Citric acid
CoA
NAD
Acetyl-CoA
CO
2
NADH
H
2
O
Oxalacetic acid
CoA
Isocitric acid
NAD
Oxoglutaric acid
CO
2
NADH
H
+
NAD
CoA
Succinyl-CoA
NADH
H
+
CO
2
P
i
GDP
CoA
GTP
L-Malic acid
NAD
NADH
H
+
ATP
HCO
3
-
ADP
P
i
cis-Aconitic acid
H
2
O
H
2
O
Isocitric acid
NADP
Oxoglutaric acid
NADPH
NADPH
2-Hydroxyglutarate
NADP
NADP
Oxoglutaric acid
NADPH
Q
FAD
QH
2
FADH
2
H
2
O
O
2
Oxoglutaric acid
L-Proline
CO
2
Succinic acid
4-Hydroxyproline
NADP
NADPH
Oxygen
Thiamine
pyrophosphate
Lipoamide
FAD
Magnesium
Thiamine
pyrophosphate
Lipoamide
FAD
Biotin
Manganese
Fe2+
Ascorbic acid
FAD
Glycolysis
Mitochondrial
Electron
Transport Chain
Cytoplasmic
aconitate
hydratase
Succinic acid
4Fe-4S
4Fe-4S
Magnesium
FAD
2Fe-2S
Fumaric acid
4Fe-4S
Inner mitochondrial membrane
Mitochondrial intermembrane
space
Cytosol
Mitochondrial matrix
Mitochondrion
Intracellular Space
Inner mitochondrial membrane
Outer mitochondrial membrane
Epigenetic Regulation
Oncogene Activation,
Tumour-suppressor
inactivation
Pseudo-Hypoxia
Mutant FH
Citric acid
Isocitric acid
Oxoglutaric acid
2-Hydroxyglutarate
TCA cycle
Cytoplasmic aconitate
hydratase
Isocitrate dehydrogenase
[NADP] cytoplasmic
mutIDH1
Fumaric acid
prolyl hydroxylase
Hypoxia inducible factor
1-alpha
Methylcytosine dioxygenase
TET1
Lysine-specific demethylase
2A