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Pathway Description
NAD+ Signalling Pathway (Cancer)
Homo sapiens
Signaling Pathway
Created: 2018-08-07
Last Updated: 2019-08-16
NAD+-dependent signalling pathways regulate many fundamental processes such as DNA repair, DNA transcription, cell proliferation, cell survival, cell cycle progression, apoptosis, and metabolism. These pathways are all linked to cancer development. Degradation of NAD will activate various biosynthetic pathways, which are crucial for incessant cancer cell proliferation.
References
NAD+ Signalling Pathway (Cancer) References
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Pubmed: 19109034
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Pubmed: 16710414
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Pubmed: 1657151
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Pubmed: 2843525
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Pubmed: 22842230
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