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Table of Primary Pathways
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Unknown
Unknown
Neutral and
basic amino
acid transport
protein rBAT
B(0,+)-type
amino acid
transporter 1
Neutral and
basic amino
acid transport
protein rBAT
B(0,+)-type
amino acid
transporter 1
Tryptophan
2,3-dioxygenase
Kynurenine
3-monooxygenase
Kynureninase
3-
hydroxyanthranilate
3,4-dioxygenase
Quinolinic acid
L-Tryptophan
L-Tryptophan
L-Tryptophan
L-Tryptophan
Quinolinic acid
L-Kynurenine
Hydroxykynurenine
3-Hydroxyanthranilic acid
Heme
FAD
NMDA receptor
agonist,
excessive
glutamate
release, lipid
peroxidation
Pyrophosphate
Hepatocyte
Intestinal Lumen
Intestinal Epithelial Cell
Intestinal Epithelial Cell
Tryptophan obtained from
high protein foods
Cytosol
Unknown
Unknown
SLC3A1
SLC7A9
SLC3A1
SLC7A9
TDO2
KMO
KYNU
HAAO
Quinolinic acid
L-Tryptophan
L-Tryptophan
L-Tryptophan
L-Tryptophan
Quinolinic acid
L-Kynurenine
Hydroxykynurenine
3-
Hydroxyanthranilic
acid
NMDA receptor
agonist,
excessive
glutamate
release, lipid
peroxidation