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Insulin
Insulin
receptor
Carnitine O-
palmitoyltransferase
1, liver
isoform
Long-chain
fatty acid
transport
protein 1
Mitochondrial
carnitine/acylcarnitine
carrier protein
Organic
cation/carnitine
transporter 2
Long-chain-
fatty-acid--
CoA ligase 1
Carnitine O-
palmitoyltransferase
2,
mitochondrial
Malonyl-CoA
decarboxylase,
mitochondrial
Carnitine O-
acetyltransferase
Malonyl-CoA
Palmitoyl-CoA
Acetyl-CoA
Palmitoyl-CoA
Palmitic acid
NADH
Palmitic acid
L-
Palmitoylcarnitine
L-
Palmitoylcarnitine
L-Carnitine
L-Carnitine
ATP
CoA
AMP
PP
i
CoA
L-Carnitine
CoA
ATP
HCO
3
-
H
+
ADP
P
i
H
+
P
i
ADP
H
2
O
Acetyl-CoA
ATP
CO
2
L-Carnitine
L-
Acetylcarnitine
CoA
a biotinylated
[BCCP dimer]
carboxylated-
biotinylated
[BCCP dimer]
Mitochondrial
Beta-Oxidation
of Long Chain
Saturated Fatty
Acids
Activation of
peroxisomal FA
Ooxidation
Insulin
Signalling
TCA Cycle
Mitochondrial
Electron
Transport Chain
Acetyl-coenzyme
A carboxylase
carboxyl
transferase
subunit beta
Acetyl-coenzyme
A carboxylase
carboxyl
transferase
subunit alpha
Biotin
carboxylase
Biotin carboxyl
carrier protein
of acetyl-CoA
carboxylase
Magnesium
Cytosol
Mitochondrial Outer Membrane
Mitochondrial Inter-membrane
Space
Mitochondrial Inner Membrane
Mitochondrial Matrix
Mitochondria
Unknown
INSR
CPT1A
SLC27A1
SLC25A20
SLC22A5
ACSL1
CPT2
MLYCD
CRAT
Malonyl-CoA
Palmitoyl-CoA
Acetyl-CoA
Palmitoyl-CoA
Palmitic acid
NADH
Palmitic acid
L-
Palmitoylcarnitine
L-
Palmitoylcarnitine
L-Carnitine
L-Carnitine
Adenosine
triphosphate
Coenzyme A
Adenosine
monophosphate
Pyrophosphate
Coenzyme A
L-Carnitine
Coenzyme A
Adenosine
triphosphate
Hydrogen
carbonate
Hydrogen Ion
Adenosine
diphosphate
Phosphate
Hydrogen Ion
Phosphate
Adenosine
diphosphate
Water
Acetyl-CoA
Adenosine
triphosphate
Carbon dioxide
L-Carnitine
L-
Acetylcarnitine
Coenzyme A
a biotinylated
[BCCP dimer]
carboxylated-
biotinylated
[BCCP dimer]
Mitochondrial
Beta-Oxidation
of Long Chain
Saturated Fatty
Acids
Activation of
peroxisomal FA
Ooxidation
Insulin
Signalling
TCA Cycle
Mitochondrial
Electron
Transport Chain
accD
accA
accC
accB
INSR
CPT1A
SLC27A1
SLC25A20
SLC22A5
ACSL1
CPT2
MLYCD
CRAT
MalyCoA
COA16:0
Ac-CoA
COA16:0
16:0
NADH
16:0
L-Plmtc
L-Plmtc
L-Carnt
L-Carnt
ATP
CoA
AMP
PP
i
CoA
L-Carnt
CoA
ATP
HCO
3
-
H
+
ADP
P
i
H
+
P
i
ADP
H
2
O
Ac-CoA
ATP
CO
2
L-Carnt
L-Alcar
CoA
ABBD
CBBD
PW000173
A o p F
PW000454
PW002364
PW000165
accD
accA
accC
accB
Mg2+
Cytosol
Mitochondrial Outer Membrane
Mitochondrial Inter-membrane
Space
Mitochondrial Inner Membrane
Mitochondrial Matrix