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Adenine
intestinal
membrane
transporter
Adenine
membrane
transporter
Guanine
intestinal
membrane
transporter
Guanine
membrane
transporter
Xanthosine
tranporter
Purine
nucleoside
phosphorylase
Adenosine
deaminase
Purine
nucleoside
phosphorylase
Xanthine
dehydrogenase/oxidase
Guanine
deaminase
Purine
nucleoside
phosphorylase
Xanthosine
Adenine
Adenine
Adenine
Guanine
Guanine
Guanine
Guanine
Xanthosine
Adenosine
P
i
Ribose 1-phosphate
H
2
O
Inosine
NH
3
P
i
Hypoxanthine
Ribose 1-phosphate
O
2
H
2
O
Xanthine
H
2
O
2
H
2
O
NH
3
P
i
Ribose 1-phosphate
Zinc (II) ion
FAD
2Fe-2S
Molybdopterin
Zinc (II) ion
Adenine
Renal failure
Cardiovascular
disease
Hepatocyte
Intestinal Lumen
Intestinal epithelial cells
Intestinal epithelial cells
Adenine and guanine are
obtained from red meats
Cytosol
Unknown
Unknown
Unknown
Unknown
Unknown
PNP
ADA
PNP
XDH
GDA
PNP
Xanthosine
Adenine
Adenine
Adenine
Guanine
Guanine
Guanine
Guanine
Xanthosine
Adenosine
Phosphate
Ribose
1-phosphate
Water
Inosine
Ammonia
Phosphate
Hypoxanthine
Ribose
1-phosphate
Oxygen
Water
Xanthine
Hydrogen
peroxide
Water
Ammonia
Phosphate
Ribose
1-phosphate
Adenine
Renal failure
Cardiovascular
disease