Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
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Xanthine dehydrogenase/oxidase Allopurinol transporter Allopurinol transporter Purine nucleoside phosphorylase Adenosine deaminase Purine nucleoside phosphorylase Xanthine dehydrogenase/oxidase Guanine deaminase Xanthine dehydrogenase/oxidase Oxypurinol Allopurinol Uric acid Allopurinol Allopurinol Allopurinol Adenosine Pi Adenine Ribose 1-phosphate H2O Inosine NH3 Pi Hypoxanthine Ribose 1-phosphate O2 H2O Xanthine H2O2 Guanine H2O NH3 NAD H2O NADH Zinc (II) ion FAD 2Fe-2S Molybdopterin Zinc (II) ion FAD 2Fe-2S Molybdopterin Gout FAD 2Fe-2S Molybdopterin Hepatocyte Cytosol Allopurinol can be converted into oxypurinol which is an active metabolite Allopurionol and oxypurinol inhibits xanthine oxidase/dehydrogenase leading to reduced uric acid production Uric acid produces symptoms of gout, therefore, low levels of uric acid reduce incidence of gout symptoms Liver
XDH Unknown Unknown PNP ADA PNP XDH GDA XDH Oxypurinol Allopurinol Uric acid Allopurinol Allopurinol Allopurinol Adenosine Phosphate Adenine Ribose 1-phosphate Water Inosine Ammonia Phosphate Hypoxanthine Ribose 1-phosphate Oxygen Water Xanthine Hydrogen peroxide Guanine Water Ammonia NAD Water NADH Gout