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Unknown Unknown GTP cyclohydrolase GTP cyclohydrolase GTP cyclohydrolase GTP cyclohydrolase 6-pyruvoyl tetrahydrobiopterin synthase Sepiapterin reductase Sepiapterin reductase Aldose reductase Carbonyl reductase [NADPH] 1 Sepiapterin reductase Carbonyl reductase [NADPH] 1 Sepiapterin reductase Dihydrofolate reductase Sepiapterin reductase Dihydropteridine reductase Tyrosine 3-monooxygenase Aromatic-L- amino-acid decarboxylase Tryptophan 5-hydroxylase 1 Aromatic-L- amino-acid decarboxylase Guanosine triphosphate Formamidopyrimidine nucleoside triphosphate H2O 2,5-Diaminopyrimidine nucleoside triphosphate Formic acid H2O Formic acid 2,5-Diamino-6-(5'- triphosphoryl-3',4'- trihydroxy-2'-oxopentyl)- amino-4-oxopyrimidine Dihydroneopterin triphosphate H2O Dyspropterin PPPi NADP NADPH 1-hydroxy-2-Oxopropyl tetrahydropterin NADP 6-Lactoyltetrahydropterin NADPH NADP NADPH Sepiapterin NADPH 7,8-Dihydroneopterin NADP NADP NADPH NADP Tetrahydrobiopterin NADPH NADPH NADP H2O Neopterin NAD NADH Dihydrobiopterin NADPH NADP O2 L-Dopa H2O CO2 L-Tryptophan O2 4a-Hydroxytetrahydrobiopterin CO2 Zinc Zinc Zinc Zinc Zinc Pyridoxal 5'-phosphate Fe2+ Pyridoxal 5'-phosphate L-Tyrosine Dopamine 5-Hydroxy-L-tryptophan Serotonin Purine Metabolism Fe2+ Cytosol Clumsy or unusual gait, and experiences involuntary muscle contractions and uncontrolled movements (dystonia) due to low dopamine and serotonin..
Unknown Unknown GCH1 GCH1 GCH1 GCH1 PTS SPR SPR AKR1B1 CBR1 SPR CBR1 SPR DHFR SPR QDPR TH DDC TPH1 DDC Guanosine triphosphate Formamidopyrimidine nucleoside triphosphate Water 2,5- Diaminopyrimidine nucleoside triphosphate Formic acid Water Formic acid 2,5-Diamino- 6-(5'- triphosphoryl- 3',4'- trihydroxy- 2'- oxopentyl)- amino-4- oxopyrimidine Dihydroneopterin triphosphate Water Dyspropterin PPPi NADP NADPH 1-hydroxy-2- Oxopropyl tetrahydropterin NADP 6- Lactoyltetrahydropterin NADPH NADP NADPH Sepiapterin NADPH 7,8- Dihydroneopterin NADP NADP NADPH NADP Tetrahydrobiopterin NADPH NADPH NADP Water Neopterin NAD NADH Dihydrobiopterin NADPH NADP Oxygen L-Dopa Water Carbon dioxide L-Tryptophan Oxygen 4a- Hydroxytetrahydrobiopterin Carbon dioxide L-Tyrosine Dopamine 5-Hydroxy-L- tryptophan Serotonin Purine Metabolism
GCH1 GCH1 GCH1 GCH1 PTS SPR SPR AKR1B1 CBR1 SPR CBR1 SPR DHFR SPR QDPR TH DDC TPH1 DDC GTP Formami H2O 25DNT Formate H2O Formate DTTOAO DHNTP H2O Dysprop PPPi NADP NADPH 1H2OT NADP 6-Lthpn NADPH NADP NADPH Sepiapt NADPH 7,8DHPN NADP NADP NADPH NADP BH4 NADPH NADPH NADP H2O Neopter NAD NADH BH3 NADPH NADP O2 L-Dopa H2O CO2 Trp O2 4aHtHbp CO2 Zinc Zinc Zinc Zinc Zinc Pyr-5'P Fe2+ Pyr-5'P Tyr LDP 5-HTP 5-HT PW000052 Fe2+ Cytosol Clumsy or unusual gait, and experiences involuntary muscle contractions and uncontrolled movements (dystonia) due to low dopamine and serotonin..
GCH1 GCH1 GCH1 GCH1 PTS SPR SPR AKR1B1 CBR1 SPR CBR1 SPR DHFR SPR QDPR TH DDC TPH1 DDC GTP Formami H2O 25DNT Formate H2O Formate DTTOAO DHNTP H2O Dysprop PPPi NADP NADPH 1H2OT NADP 6-Lthpn NADPH NADP NADPH Sepiapt NADPH 7,8DHPN NADP NADP NADPH NADP BH4 NADPH NADPH NADP H2O Neopter NAD NADH BH3 NADPH NADP O2 L-Dopa H2O CO2 Trp O2 4aHtHbp CO2 Tyr LDP 5-HTP 5-HT PW000052