Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
Loader

Loading Pathway...

Y+L amino acid transporter 2 4F2 cell-surface antigen heavy chain Y+L amino acid transporter 1 4F2 cell-surface antigen heavy chain Solute carrier family 22 member 5 SLC6A19 SLC6A19 SLC6A19 Sodium- and chloride- dependent creatine transporter 1 L-amino-acid oxidase Tyrosine aminotransferase Phenylalanine- 4-hydroxylase Aspartate aminotransferase, cytoplasmic Tyrosine aminotransferase L-amino-acid oxidase 4- hydroxyphenylpyruvate dioxygenase Homogentisate 1,2-dioxygenase Maleylacetoacetate isomerase Fumarylacetoacetase Aromatic-L- amino-acid decarboxylase Amine oxidase [flavin- containing] A Aldehyde dehydrogenase, dimeric NADP-preferring Acyl-coenzyme A synthetase ACSM1, mitochondrial Glycine N-acyltransferase Phenylpyruvate Decarboxylase Cytochrome P450 3A4 Y+L amino acid transporter 1 L-Tyrosine Fumaric acid Acetoacetic acid Mandelic acid Phenylacetic acid Phenylpyruvic acid Phenylpyruvic acid L-Phenylalanine L-Phenylalanine L-Phenylalanine L-Phenylalanine L-Phenylalanine Phenylacetylglutamine Glycine Glycine Glycine Glycine L-Phenylalanine Phenylpyruvic acid Phenylacetic acid Mandelic acid Phenylacetylglutamine H2O O2 NH3 H2O2 Oxoglutaric acid L-Glutamic acid L-erythro- tetrahydrobiopterin O2 4a- Hydroxytetrahydrobiopterin Oxoglutaric acid 4- Hydroxyphenylpyruvic acid L-Glutamic acid Oxoglutaric acid L-Glutamic acid H2O O2 NH3 H2O2 O2 Homogentisic acid CO2 O2 Maleylacetoacetic acid 4- Fumarylacetoacetic acid H2O H+ Phenylethylamine CO2 H2O O2 Phenylacetaldehyde Ammonium H2O2 NADP H2O NADPH H+ ATP CoA Phenylacetyl-CoA PPi AMP L-Glutamine CoA O2 NADPH H+ H2O NADP Fe2+ Fe3+ Calcium Magnesium Magnesium Catecholamine Biosynthesis Tyrosine Metabolism Citric Acid Cycle Aspartate aminotransferase, cytoplasmic Phenylacetylglutamine Pyridoxal 5'-phosphate FAD Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate Pyridoxal 5'-phosphate FAD Iron Mandelic acid Phenylacetic acid Pyridoxal 5'-phosphate FAD Heme Cytosol Blood Vessel Hepatocyte Lysosome Behavioural problems, psychiatric disorders and seizures. Phenylpyruvic acid, Mandelic acid, Phenylacetic acid, and Phenylacetylglutamine are produced in high concentration in Phenylketonuria Phenylalanine is ingested by eating foods like meat, eggs, nuts, etc. Liver Glycine is unable to bind to NMDA receptors due to Phenylalanine antagonistically binding to the sites. This leads to a high concentration of glycine in the blood and urine Kidney Bladder Kidney
SLC7A6 SLC3A2 SLC7A7 SLC3A2 SLC22A5 SLC6A19 SLC6A19 SLC6A19 SLC6A8 IL4I1 TAT PAH GOT1 TAT IL4I1 HPD HGD GSTZ1 FAH DDC MAOA ALDH3A1 ACSM1 GLYAT Unknown CYP3A4 SLC7A7 L-Tyrosine Fumaric acid Acetoacetic acid Mandelic acid Phenylacetic acid Phenylpyruvic acid Phenylpyruvic acid L-Phenylalanine L-Phenylalanine L-Phenylalanine L-Phenylalanine L-Phenylalanine Phenylacetylglutamine Glycine Glycine Glycine Glycine L-Phenylalanine Phenylpyruvic acid Phenylacetic acid Mandelic acid Phenylacetylglutamine Water Oxygen Ammonia Hydrogen peroxide Oxoglutaric acid L-Glutamic acid L-erythro- tetrahydrobiopterin Oxygen 4a- Hydroxytetrahydrobiopterin Oxoglutaric acid 4- Hydroxyphenylpyruvic acid L-Glutamic acid Oxoglutaric acid L-Glutamic acid Water Oxygen Ammonia Hydrogen peroxide Oxygen Homogentisic acid Carbon dioxide Oxygen Maleylacetoacetic acid 4- Fumarylacetoacetic acid Water Hydrogen Ion Phenylethylamine Carbon dioxide Water Oxygen Phenylacetaldehyde Ammonium Hydrogen peroxide NADP Water NADPH Hydrogen Ion Adenosine triphosphate Coenzyme A Phenylacetyl-CoA Pyrophosphate Adenosine monophosphate L-Glutamine Coenzyme A Oxygen NADPH Hydrogen Ion Water NADP Catecholamine Biosynthesis Tyrosine Metabolism Citric Acid Cycle GOT1 Phenylacetylglutamine Mandelic acid Phenylacetic acid