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Mitochondrial
pyruvate
carrier 1
Neutral amino
acid
transporter A
Unknown
Monocarboxylate
transporter 11
Alanine--tRNA
ligase,
cytoplasmic
Alanine
aminotransferase
1
Pyruvate
carboxylase,
mitochondrial
Serine--
pyruvate
aminotransferase
Alanine--tRNA
ligase,
mitochondrial
L-Alanine
Oxalacetic acid
Pyruvic acid
Pyruvic acid
L-Alanine
Oxoglutaric acid
Oxoglutaric acid
Pyruvic acid
ATP
AMP
PP
i
L-Glutamic acid
ATP
HCO
3
-
ADP
P
i
L-Alanine
Glyoxylic acid
Glycine
ATP
AMP
PP
i
Pyridoxal
5'-phosphate
Pyridoxal
5'-phosphate
Zinc (II) ion
tRNA(Ala)
L-Alanyl-
tRNA(Ala)
tRNA(Ala)
L-Alanyl-
tRNA(Ala)
Selenoamino
Acid Metabolism
Citric Acid
Cycle
Cytosol
Biotin
Manganese
Zinc (II) ion
Mitochondria
Intracellular Space
Intermembrane space
Mitochondrial Matrix
Symptoms include ataxia,
lactic acidosis, mental
retardation, metabolic
acidosis, siezures, and
dyspnea.
Mitochondria
MPC1
SLC1A4
Unknown
SLC16A11
AARS
GPT
PC
AGXT
AARS2
L-Alanine
Oxalacetic acid
Pyruvic acid
Pyruvic acid
L-Alanine
Oxoglutaric
acid
Oxoglutaric
acid
Pyruvic acid
Adenosine
triphosphate
Adenosine
monophosphate
Pyrophosphate
L-Glutamic acid
Adenosine
triphosphate
Hydrogen
carbonate
Adenosine
diphosphate
Phosphate
L-Alanine
Glyoxylic acid
Glycine
Adenosine
triphosphate
Adenosine
monophosphate
Pyrophosphate
tRNA(Ala)
L-Alanyl-
tRNA(Ala)
tRNA(Ala)
L-Alanyl-
tRNA(Ala)
Selenoamino
Acid Metabolism
Citric Acid
Cycle