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Aldose reductase Sorbitol dehydrogenase 14 kDa phosphohistidine phosphatase Hexokinase-1 Mannose-6- phosphate isomerase Hexokinase-1 Phosphomannomutase 1 6- phosphofructokinase, liver type Fructose-1,6- bisphosphatase 1 Mannose-1- phosphate guanyltransferase beta Fructose- bisphosphate aldolase B GDP-mannose 4,6 dehydratase GDP-L-fucose synthase Fucose-1- phosphate guanylyltransferase L-fucose kinase Ketohexokinase Triosephosphate isomerase Fructose- bisphosphate aldolase A 6- phosphofructo- 2- kinase/fructose- 2,6- bisphosphatase 1 α-D-Glucose Fructose 6-phosphate Dihydroxyacetone phosphate NADP Sorbitol NADPH NAD D-Fructose NADH β-D-Fructose 2-phosphate H2O Pi ATP ADP Mannose 6-phosphate D-Mannose ATP ADP D-Mannose 1-phosphate ATP Fructose 1,6-bisphosphate ADP H2O Pi GTP Guanosine diphosphate mannose PPi D-Glyceraldehyde 3-phosphate GDP-4-Dehydro-6-deoxy-D- mannose H2O GDP-L-fucose NADP NADPH Fucose 1-phosphate GTP PPi L-Fucose ADP ATP ADP Glyceraldehyde D-Fructose 2,6-bisphosphate H2O Pi Zinc (II) ion NADP Fructose 1-phosphate ATP Galactose Metabolism Glycolysis Glycolysis Amino Sugar Metabolism Magnesium Zinc (II) ion Magnesium Magnesium Mitochondrial Membrane Mitochondria Intracellular Space Liver Hepatic Liver Cell Kidney Brain Symptoms of this disorder include hypoglycemia, abdominal pain, vomiting, After repeated ingestion of fructose, liver and kidney damage can occur
Mitochondria AKR1B1 SORD PHPT1 HK1 MPI HK1 PMM1 PFKL FBP1 GMPPB ALDOB GMDS TSTA3 FPGT FUK KHK TPI1 ALDOA PFKFB1 α-D-Glucose Fructose 6-phosphate Dihydroxyacetone phosphate NADP Sorbitol NADPH NAD D-Fructose NADH β-D-Fructose 2-phosphate Water Phosphoric acid Adenosine triphosphate Adenosine diphosphate Mannose 6-phosphate D-Mannose Adenosine triphosphate Adenosine diphosphate D-Mannose 1-phosphate Adenosine triphosphate Fructose 1,6- bisphosphate Adenosine diphosphate Water Phosphate Guanosine triphosphate Guanosine diphosphate mannose Pyrophosphate D- Glyceraldehyde 3-phosphate GDP-4- Dehydro-6- deoxy-D- mannose Water GDP-L-fucose NADP NADPH Fucose 1-phosphate Guanosine triphosphate Pyrophosphate L-Fucose Adenosine diphosphate Adenosine triphosphate Adenosine diphosphate Glyceraldehyde D-Fructose 2,6- bisphosphate Water Phosphate Fructose 1-phosphate Adenosine triphosphate Galactose Metabolism Glycolysis Glycolysis Amino Sugar Metabolism
AKR1B1 SORD PHPT1 HK1 MPI HK1 PMM1 PFKL FBP1 GMPPB ALDOB GMDS TSTA3 FPGT FUK KHK TPI1 ALDOA PFKFB1 a-D-Glc Fru6P Dhapp NADP Srbitol NADPH NAD Fru NADH βDF2P H2O Pi ATP ADP Man-6P Man ATP ADP M1P ATP Fru1,6P ADP H2O Pi GTP GDPMan PPi Glyc3P G4D6DMn H2O GDP-Fuc NADP NADPH Fuc-1P GTP PPi Fucose ADP ATP ADP Glycald Fru2,6P H2O Pi Zinc NADP Fru-1P ATP PW000159 PW000146 PW000146 PW000008 Mg2+ Zinc Mg2+ Mg2+ Mitochondrial Membrane Mitochondria Intracellular Space Liver Hepatic Liver Cell Kidney Brain Symptoms of this disorder include hypoglycemia, abdominal pain, vomiting, After repeated ingestion of fructose, liver and kidney damage can occur
Mitochondria AKR1B1 SORD PHPT1 HK1 MPI HK1 PMM1 PFKL FBP1 GMPPB ALDOB GMDS TSTA3 FPGT FUK KHK TPI1 ALDOA PFKFB1 a-D-Glc Fru6P Dhapp NADP Srbitol NADPH NAD Fru NADH βDF2P H2O PhosfrA ATP ADP Man-6P Man ATP ADP M1P ATP Fru1,6P ADP H2O Pi GTP GDPMan Ppi Glyc3P G4D6DMn H2O GDP-Fuc NADP NADPH Fuc-1P GTP Ppi Fucose ADP ATP ADP Glycald Fru2,6P H2O Pi Fru-1P ATP PW000159 PW000146 PW000146 PW000008