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CDP-
diacylglycerol-
-inositol 3-
phosphatidyltransferase
Synaptojanin-1
Phosphatidylinositol-
4,5-
bisphosphate
3-kinase
catalytic
subunit alpha
isoform
Phosphatidylinositol
3-kinase
regulatory
subunit alpha
Phosphatidylinositol
3-kinase
catalytic
subunit type 3
Phosphoinositide
3-kinase
regulatory
subunit 4
Beclin-1
Activating
molecule in
BECN1-regulated
autophagy
protein 1
1-
phosphatidylinositol-
3-phosphate
5-kinase
Polyphosphoinositide
phosphatase
Protein VAC14
homolog
Phosphatidylinositol
4-phosphate
5-kinase type-1
alpha
Phosphatidylinositol
4-phosphate
5-kinase type-1
alpha
Synaptojanin-1
Type II
inositol 3,4-
bisphosphate
4-phosphatase
Phosphatidylinositol-
5-phosphate
4-kinase type-2
alpha
Phosphatidylinositol
3,4,5-
trisphosphate
5-phosphatase 1
Phosphatidylinositol
4-phosphate
5-kinase type-1
alpha
72 kDa inositol
polyphosphate
5-phosphatase
Synaptojanin-1
Synaptojanin-1
Phosphatidylinositol
4-kinase alpha
Phosphatidylinositol
4-phosphate
3-kinase C2
domain-
containing
subunit alpha
Phosphatidylinositol
4,5-
bisphosphate
3-kinase
catalytic
subunit alpha
isoform
Phosphatidylinositol
3,4,5-
trisphosphate
3-phosphatase
and dual-
specificity
protein
phosphatase
PTEN
Phosphatidylinositol
4,5-
bisphosphate
3-kinase
catalytic
subunit alpha
isoform
1-
phosphatidylinositol
4,5-
bisphosphate
phosphodiesterase
beta-1
Phosphatidylinositol
4-phosphate
5-kinase type-1
alpha
Phosphatidylinositol
3,4,5-
trisphosphate
5-phosphatase 1
72 kDa inositol
polyphosphate
5-phosphatase
Synaptojanin-1
Phosphatidylinositol
3,4,5-
trisphosphate
5-phosphatase 1
Phosphatidylinositol-
5-phosphate
4-kinase type-2
alpha
Synaptojanin-1
Polyphosphoinositide
phosphatase
Phosphatidylinositol
4-phosphate
5-kinase type-1
alpha
myo-Inositol
Inositol 1,4,5-trisphosphate
CDP-DG(16:0/18:1(9Z))
PI(16:0/18:1(9Z))
Cytidine monophosphate
PIP(18:1(9Z)/16:0)
H
2
O
P
i
ATP
ADP
ATP
ADP
ATP
PIP2(16:0/18:1(9Z))
ADP
ATP
ADP
ATP
PIP2(16:0/18:1(9Z))
ADP
H
2
O
P
i
H
2
O
P
i
ATP
ADP
PIP3(16:0/18:1(9Z))
H
2
O
P
i
ATP
ADP
H
2
O
P
i
H
2
O
P
i
PIP[4'](16:0/18:1(9Z))
H
2
O
P
i
ATP
ADP