Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.

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Adenylate cyclase type 9 Myosin light chain kinase, smooth muscle PKA complex PKA complex Alpha-2A adrenergic receptor G protein complex Myosin LC-P Myosin light chain 3 Inositol 1,4,5- trisphosphate receptor type 1 Myosin light chain phosphatase Calmodulin Calmodulin Epinephrine Ca+ Ca+ ATP cAMP Dipivefrin Ca+ Muscle Contraction Muscle Relaxation G(i) protein signalling cascade Magnesium Calcium Manganese Sarcoplasmic Reticulum Cytosol Ciliary Smooth Muscle Cell Epinephrine binds to alpha-2 adrenergic receptor. Activation of the alpha-2 adrenergic receptor activates the G(i) protein signalling cascade. There is an overall increase in calcium levels in the cytosol. Increased calcium is able to bind readily to calmodulin. The high concentration of myosin LC-P allows for muscle contraction to occur Anterior Chamber Actin Myosin Inhibition of adenylyl cyclase, decreasing the formation of intracellular cAMP. Dipivefrin is a prodrug for epinephrine. Dipivefrin is administered as an eye drop Myosin binds to actin causing the sarcomere filaments to slide leading to muscle contraction
ADCY9 MYLK PRKAR1A PRKAR2A ADRA2A GNAI1 MYL3 MYL3 ITPR1 PPP1CB CALM1 CALM1 Epinephrine Calcium Calcium Adenosine triphosphate cAMP Dipivefrin Calcium Muscle Contraction Muscle Relaxation G(i) protein signalling cascade