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Gamma- aminobutyric acid receptor subunit beta-2 Gamma- aminobutyric acid receptor subunit gamma-2 Gamma- aminobutyric acid type B receptor Gamma- aminobutyric acid receptor subunit alpha-1 Adenylate cyclase type 1 Vesicular inhibitory amino acid transporter Voltage- dependent P/Q-type calcium channel subunit alpha-1A Glutamate decarboxylase 1 γ-Aminobutyric acid cAMP γ-Aminobutyric acid Ca+ Chlordiazepoxide L-Glutamic acid Cl- γ-Aminobutyric acid Ca+ Chlordiazepoxide Chlordiazepoxide Cl- CO2 ATP PPi Magnesium Pyridoxal 5'-phosphate Gi/o signalling Glutamate Metabolism Hyperpolarization Hyperpolarization leading to reduced depolarization and excitability. Decreasing neuronal excitability has a sedative effect Presynaptic Neuron Post Synaptic Neuron Synaptic Vesicle GABA binds to the GABA(a) receptor in between the alpha and beta subunits. Chlordiazepoxide binds the GABA(a) receptor between the gamma and alpha subunits. Cytosol Cytosol Synapse Chlordiazepoxide is a ligand for the GABA benzodiazepine binding site. Chlordiazepoxide is administered as an oral capsule.
GABRB2 GABRG2 GABBR2 GABRA1 ADCY1 SLC32A1 CACNA1A GAD1 γ-Aminobutyric acid cAMP γ-Aminobutyric acid Calcium Chlordiazepoxide L-Glutamic acid Chloride ion γ-Aminobutyric acid Calcium Chlordiazepoxide Chlordiazepoxide Chloride ion Carbon dioxide Adenosine triphosphate Pyrophosphate Gi/o signalling Glutamate Metabolism Hyperpolarization
GABRB2 GABRG2 GABBR2 GABRA1 ADCY1 SLC32A1 CACNA1A GAD1 GABA cAMP GABA Ca+ Cdp Glu Cl- GABA Ca+ Cdp Cdp Cl- CO2 ATP PPi Mg2+ Pyr-5'P Gi/ sig PW000003 Hyper Hyperpolarization leading to reduced depolarization and excitability. Decreasing neuronal excitability has a sedative effect Presynaptic Neuron Post Synaptic Neuron Synaptic Vesicle GABA binds to the GABA(a) receptor in between the alpha and beta subunits. Chlordiazepoxide binds the GABA(a) receptor between the gamma and alpha subunits. Cytosol Cytosol Synapse Chlordiazepoxide is a ligand for the GABA benzodiazepine binding site. Chlordiazepoxide is administered as an oral capsule.