Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
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Gamma- aminobutyric acid receptor subunit beta-2 Gamma- aminobutyric acid receptor subunit gamma-2 Gamma- aminobutyric acid type B receptor Gamma- aminobutyric acid receptor subunit alpha-1 Adenylate cyclase type 1 Vesicular inhibitory amino acid transporter Voltage- dependent P/Q-type calcium channel subunit alpha-1A Multidrug resistance- associated protein 4 Solute carrier family 22 member 11 Glutamate decarboxylase 1 γ-Aminobutyric acid cAMP γ-Aminobutyric acid Ca+ Nordiazepam L-Glutamic acid Cl- γ-Aminobutyric acid Ca+ Nordiazepam Prazepam Prazepam Prazepam Cl- CO2 ATP PPi Nordiazepam Magnesium Pyridoxal 5'-phosphate Gi/o signalling Glutamate Metabolism Hyperpolarization Hyperpolarization leading to reduced depolarization and excitability. Decreasing neuronal excitability has a sedative effect Presynaptic Neuron Post Synaptic Neuron Synaptic Vesicle GABA binds to the GABA(a) receptor in between the alpha and beta subunits. Nordiazepam binds to an allosteric site of the GABA(A) receptor between the gamma and alpha subunits. It is a ligand for the benzodiazepine binding site. Cytosol Cytosol Synapse Hepatocyte Endoplasmic Reticulum Prazepam is administered as an oral tablet
Endoplasmic Reticulum GABRB2 GABRG2 GABBR2 GABRA1 ADCY1 SLC32A1 CACNA1A ABCC4 SLC22A11 GAD1 γ-Aminobutyric acid cAMP γ-Aminobutyric acid Calcium Nordiazepam L-Glutamic acid Chloride ion γ-Aminobutyric acid Calcium Nordiazepam Prazepam Prazepam Prazepam Chloride ion Carbon dioxide Adenosine triphosphate Pyrophosphate Nordiazepam Gi/o signalling Glutamate Metabolism Hyperpolarization