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Pathway Description
Prednisolone Phosphate Action Pathway
Homo sapiens
Drug Action Pathway
Created: 2023-06-07
Last Updated: 2023-10-25
Prednisolone phosphate, a corticosteroid is administered as prednisolone sodium phosphate orally and ophthalmically. It is converted to active metabolite, prednisolone by hydrolysis which can be reversibly converted to prednisone in the liver.
References
Prednisolone Phosphate Pathway References
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Pubmed: 1874907
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Pubmed: 23018468
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Pubmed: 6237151
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Pubmed: 29126136
Wishart, D., Knox, C., Guo, A., Shrivastava, S., Hassanali, M., Stothard, P., . . . Woolsey, J. (2005, June). Prednisolone phosphate. Retrieved June 7, 2023, from https://go.drugbank.com/drugs/DB00215
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Pubmed: 2512924
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Pubmed: 1734857
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Pubmed: 7925341
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Pubmed: 11281454
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Pubmed: 11780052
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Pubmed: 9305847
Jakobsson PJ, Thoren S, Morgenstern R, Samuelsson B: Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target. Proc Natl Acad Sci U S A. 1999 Jun 22;96(13):7220-5. doi: 10.1073/pnas.96.13.7220.
Pubmed: 10377395
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Pubmed: 10760517
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Pubmed: 1902577
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Pubmed: 1385416
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Pubmed: 14702039
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Pubmed: 8274401
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