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Pathway Description
Promazine Mechanism of Action Action Pathway
Homo sapiens
Drug Action Pathway
Created: 2023-07-13
Last Updated: 2023-11-27
Promazine is used as an adjunct for short term treatment of moderate and severe psychomotor agitation. It is also used to treat agitation or restlessness in the elderly. Promazine is an antagonist at types 1, 2, and 4 dopamine receptors, 5-HT receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors, and histamine H1-receptors. Promazine's antipsychotic effect is due to antagonism at dopamine and serotonin type 2 receptors
References
Promazine Mechanism of Action Pathway References
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