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Pathway Description
Escitalopram Mechanism of Action Action Pathway New
Homo sapiens
Drug Action Pathway
Created: 2023-07-18
Last Updated: 2023-11-27
Escitalopram is the therapeutic active S- enantiomer of citalopram. It is classified as a selective serotonin reuptake inhibitor used to treat depression and anxiety. It's mechanism of action it to bind selectively bind to the sodium dependent serotonin transporter and blocking the recycling of serotonin from the synapse. As serotonin accumulates it restores the serotonergic function of the 5-hydroxytryptamine 1A receptor leading to decreased anxiety and depressive moods. Escitalopram is one of the safest SSRI treatments as it has the highest degree of selectivity for the serotonin transporter (SERT) and therefore doesn't bind to other off-target functions. Following administration, it has a high bio-availability also making it an ideal drug to treat anxiety and depression. It is mainly administered through an oral route in the form of a tablet.
References
Escitalopram Mechanism of Action Pathway New References
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