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Pathway Description
Mesoridazine Dopamine Antagonist Action Pathway
Homo sapiens
Drug Action Pathway
Created: 2023-07-20
Last Updated: 2023-11-27
Mesoridazine, the besylate salt of a metabolite of thioridazine, is a phenothiazine tranquilizer and a first generation typical antipsychotic. Based upon animal studies, mesoridazine, as with other phenothiazines, acts indirectly on reticular formation, whereby neuronal activity into reticular formation is reduced without affecting its intrinsic ability to activate the cerebral cortex.
References
Mesoridazine Dopamine Antagonist Pathway References
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Pubmed: 7916667
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Pubmed: 8302271
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Pubmed: 3131741
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Pubmed: 3127824
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