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Pathway Description
Chlorprothixene Dopamine Antagonist Action Pathway
Homo sapiens
Drug Action Pathway
Created: 2023-07-28
Last Updated: 2023-11-27
Chlorprothixene is a thioxanthene antipsychotic. Chlorprothixene blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.
References
Chlorprothixene Dopamine Antagonist Pathway References
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Pubmed: 2144334
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Pubmed: 1975640
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