Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
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D(2) dopamine receptor Voltage- dependent P/Q-type calcium channel subunit alpha-1A Voltage- dependent L-type calcium channel subunit beta-1 Voltage- dependent calcium channel subunit alpha-2/delta-2 Sodium- dependent dopamine transporter Synaptic vesicular amine transporter Aromatic-L- amino-acid decarboxylase Tyrosine 3-monooxygenase Dopamine Ca+ Prochlorperazine Ca+ Dopamine Dopamine Prochlorperazine Prochlorperazine L-Dopa CO2 L-Tyrosine Tetrahydrobiopterin O2 Dihydrobiopterin H2O Pyridoxal 5'-phosphate GDP Chemoreceptor trigger zone vomiting reflex Guanine nucleotide- binding protein G(s) subunit alpha isoforms short Fe2+ Cytosol Postsynaptic Neuron Presynaptic Neuron Cytosol Synaptic Vesicle Synapse Brain Blood vessel passive diffusion dopamine receptors in the chemoreceptor trigger zone is stimulated to cause nausea and vomiting Prochlorperazine acts as an antagonist to D2 receptors present in the vagus nerves from brain to gut Vomiting centre (medulla) Prochlorperazine blocks dopamine receptors in the chemoreceptor trigger zone and reduces vomiting reflex ↓ nausea and vomiting
DRD2 CACNA1A CACNB1 CACNA2D2 SLC6A3 SLC18A2 DDC TH Dopamine Calcium Prochlorperazine Calcium Dopamine Dopamine Prochlorperazine Prochlorperazine L-Dopa Carbon dioxide L-Tyrosine Tetrahydrobiopterin Oxygen Dihydrobiopterin Water Guanosine diphosphate vomiting reflex GNAS
DRD2 CACNA1A CACNB1 CACNA2D2 SLC6A3 SLC18A2 DDC TH LDP Ca+ Chlorpe Ca+ LDP LDP Chlorpe Chlorpe L-Dopa CO2 Tyr BH4 O2 BH3 H2O Pyr-5'P GDP Chemoreceptor trigger zone vom ref GNAS Fe2+ Cytosol Postsynaptic Neuron Presynaptic Neuron Cytosol Synaptic Vesicle Synapse Brain Blood vessel passive diffusion dopamine receptors in the chemoreceptor trigger zone is stimulated to cause nausea and vomiting Prochlorperazine acts as an antagonist to D2 receptors present in the vagus nerves from brain to gut Vomiting centre (medulla) Prochlorperazine blocks dopamine receptors in the chemoreceptor trigger zone and reduces vomiting reflex ↓ nausea and vomiting