Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
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Gamma- aminobutyric acid type B receptor Voltage- dependent T-type calcium channel subunit alpha-1H Voltage- dependent T-type calcium channel subunit alpha-1G Adenylate cyclase type 1 Vesicular inhibitory amino acid transporter Voltage- dependent P/Q-type calcium channel subunit alpha-1A Glutamate decarboxylase 1 γ-Aminobutyric acid cAMP γ-Aminobutyric acid Ca+ Paramethadione L-Glutamic acid γ-Aminobutyric acid Ca+ Ca+ Ca+ Paramethadione Paramethadione CO2 ATP PPi Magnesium Pyridoxal 5'-phosphate Gi/o signalling Glutamate Metabolism Hyperpolarization Hyperpolarization leading to reduced depolarization and excitability Presynaptic Neuron Post Synaptic Neuron Synaptic Vesicle Cytosol Cytosol Synapse Paramethadione binds to T-type calcium channels and inhibits calcium influx. Hyperpolarization prevents absence seizures GABA release linked with petit mal seizures Paramethadione is administered as an oral tablet
GABBR2 CACNA1H CACNA1G ADCY1 SLC32A1 CACNA1A GAD1 γ-Aminobutyric acid cAMP γ-Aminobutyric acid Calcium Paramethadione L-Glutamic acid γ-Aminobutyric acid Calcium Calcium Calcium Paramethadione Paramethadione Carbon dioxide Adenosine triphosphate Pyrophosphate Gi/o signalling Glutamate Metabolism Hyperpolarization
GABBR2 CACNA1H CACNA1G ADCY1 SLC32A1 CACNA1A GAD1 GABA cAMP GABA Ca+ Paradio Glu GABA Ca+ Ca+ Ca+ Paradio Paradio CO2 ATP PPi Mg2+ Pyr-5'P Gi/ sig PW000003 Hyper Hyperpolarization leading to reduced depolarization and excitability Presynaptic Neuron Post Synaptic Neuron Synaptic Vesicle Cytosol Cytosol Synapse Paramethadione binds to T-type calcium channels and inhibits calcium influx. Hyperpolarization prevents absence seizures GABA release linked with petit mal seizures Paramethadione is administered as an oral tablet