Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
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5- hydroxytryptamine receptor 2A Sodium- dependent serotonin transporter Voltage- dependent P/Q-type calcium channel subunit alpha-1A Voltage- dependent L-type calcium channel subunit beta-1 Voltage- dependent calcium channel subunit alpha-2/delta-2 Synaptic vesicular amine transporter Tryptophan 5-hydroxylase 1 Aromatic-L- amino-acid decarboxylase Ca+ Serotonin Serotonin Lorpiprazole Lorpiprazole Ca+ Serotonin Lorpiprazole Lorpiprazole Lorpiprazole L-Tryptophan Tetrahydrobiopterin O2 5-Hydroxy-L-tryptophan 4a-Hydroxytetrahydrobiopterin CO2 Na+ Na+ Fe2+ Pyridoxal 5'-phosphate Gq signaling cascade Synaptic Vesicle Cytosol Cytosol Presynaptic Neuron Postsynaptic Neuron Synapse ↓ major depressive symptoms Serotonin is synthesized at the raphei nuclei and stored in synaptic vesicles at the nerve terminal Lorpiprazole binds to 5HT2A where it exhibits antidepressive and antiaggressive properties Brain Raphei nuclei producing serotonergic neurons Blood vessel -blood brain barrier passive diffusion Lorpiprazole is administered orally Lorpiprazole is a serotonin antagonist and reuptake inhibitor used for the management of major depressive disorder
HTR2A SLC6A4 CACNA1A CACNB1 CACNA2D2 SLC18A2 TPH1 DDC Calcium Serotonin Serotonin Lorpiprazole Lorpiprazole Calcium Serotonin Lorpiprazole Lorpiprazole Lorpiprazole L-Tryptophan Tetrahydrobiopterin Oxygen 5-Hydroxy-L- tryptophan 4a- Hydroxytetrahydrobiopterin Carbon dioxide Sodium Sodium Gq signaling cascade
HTR2A SLC6A4 CACNA1A CACNB1 CACNA2D2 SLC18A2 TPH1 DDC Ca+ 5-HT 5-HT Lorpi Lorpi Ca+ 5-HT Lorpi Lorpi Lorpi Trp BH4 O2 5-HTP 4aHtHbp CO2 Na+ Na+ Fe2+ Pyr-5'P Gq si c Synaptic Vesicle Cytosol Cytosol Presynaptic Neuron Postsynaptic Neuron Synapse ↓ major depressive symptoms Serotonin is synthesized at the raphei nuclei and stored in synaptic vesicles at the nerve terminal Lorpiprazole binds to 5HT2A where it exhibits antidepressive and antiaggressive properties Brain Raphei nuclei producing serotonergic neurons Blood vessel -blood brain barrier passive diffusion Lorpiprazole is administered orally Lorpiprazole is a serotonin antagonist and reuptake inhibitor used for the management of major depressive disorder