Browsing Pathways
Showing 1 -
10 of 605359 pathways
SMPDB ID | Pathway Name and Description | Pathway Class | Chemical Compounds | Proteins |
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SMP0246161View Pathway |
citric acid cycle 1715867665 Practice |
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SMP0245828View Pathway |
citric acid cycleCitric acid cycle is also known as the Krebs cycle or tricarboxylic acid (TCA) cycle, is a series of chemical reactions in the cell that breaks down food molecules into carbon dioxide, water, and energy. In plants and animals (eukaryotes), these reactions take place in the matrix of the mitochondria of the cell as part of cellular respiration.
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SMP0213581View Pathway |
effect of serotonin in depression |
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SMP0174511View Pathway |
Tay-Sachs |
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SMP0174501View Pathway |
cell cyclepeptide drug
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SMP0126869View Pathway |
Metabolism and Physiological Effects of 2-Aminobenzoic acid2-Aminobenzoic acid, also known as anthranilic acid or O-aminobenzoate, belongs to the class of organic compounds known as aminobenzoic acids. These are benzoic acids containing an amine group attached to the benzene moiety. Within humans, 2-aminobenzoic acid participates in a number of enzymatic reactions. In particular, 2-aminobenzoic acid and formic acid can be biosynthesized from formylanthranilic acid through its interaction with the enzyme kynurenine formamidase. In addition, 2-aminobenzoic acid and L-alanine can be biosynthesized from L-kynurenine through its interaction with the enzyme kynureninase. It is a substrate of enzyme 2-Aminobenzoic acid hydroxylase in benzoate degradation via hydroxylation pathway (KEGG). In humans, 2-aminobenzoic acid is involved in tryptophan metabolism. Outside of the human body, 2-Aminobenzoic acid has been detected, but not quantified in several different foods, such as mamey sapotes, prairie turnips, rowals, natal plums, and hyacinth beans. This could make 2-aminobenzoic acid a potential biomarker for the consumption of these foods. 2-Aminobenzoic acid is a is a tryptophan-derived uremic toxin with multidirectional properties that can affect the hemostatic system. Uremic syndrome may affect any part of the body and can cause nausea, vomiting, loss of appetite, and weight loss. Chronic exposure of uremic toxins can lead to a number of conditions including renal damage, chronic kidney disease and cardiovascular disease. It can also cause changes in mental status, such as confusion, reduced awareness, agitation, psychosis, seizures, and coma. Kynureninase catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) (which is also known as 2-Aminobenzoic acid) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
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SMP0126603View Pathway |
CAPN3 Deficiency |
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SMP0126585View Pathway |
COVID-19 |
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SMP0126371View Pathway |
Glucogenólisis vong |
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SMP0126370View Pathway |
Glucogenólisis von gierke |
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Showing 1 -
10 of 20577 pathways