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PathWhiz ID | Pathway | Meta Data |
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PW176356 |
Sulfadimethoxine Predicted Metabolism PathwayHomo sapiens
Metabolites of sildenafil are predicted with biotransformer.
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Creator: Omolola Created On: December 07, 2023 at 15:29 Last Updated: December 07, 2023 at 15:29 |
PW145366 |
drug action
Sulfadoxine Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 15:40 Last Updated: October 07, 2023 at 15:40 |
PW176404 |
Sulfadoxine Predicted Metabolism PathwayHomo sapiens
Metabolites of Sulfadoxine are predicted with biotransformer.
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Creator: Omolola Created On: December 07, 2023 at 16:53 Last Updated: December 07, 2023 at 16:53 |
PW128416 |
drug action
Sulfamerazine Action PathwayEscherichia coli (strain K12)
Sulfamerazine is an antibacterial agent from the sulfanilamide drug class. It is indicated in the treatment of many infections like bronchitis, prostatitis, and urinary tract infections. Sulfamerazine is a competitive inhibitor of the dihydropteroate synthetase (DHPS). This enzyme is essential in the synthesis of folic acids from para-aminobenzoic acid (PABA) molecules. Sulfamerazine is bacteriostatic, it stops the growth of the bacteria by decreasing the synthesis of bacterial nucleotides and DNA. This drug is administered as an oral tablet.
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Creator: Daphnee Created On: August 28, 2023 at 12:44 Last Updated: August 28, 2023 at 12:44 |
PW145452 |
drug action
Sulfamerazine Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 15:51 Last Updated: October 07, 2023 at 15:51 |
PW176405 |
Sulfamerazine Predicted Metabolism PathwayHomo sapiens
Metabolites of Sulfamerazine are predicted with biotransformer.
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Creator: Omolola Created On: December 07, 2023 at 16:54 Last Updated: December 07, 2023 at 16:54 |
PW128452 |
drug action
Sulfameter Action PathwayEscherichia coli (strain K12)
Sulfameter, also known as sulfamethoxydiazine, is a long-acting antibacterial from the sulfonamide drug class. This drug is indicated in the treatment of leprosy, and urinary, and respiratory tract infections. It shows bacteriostatic effects against gram-positive and gram-negative bacteria. Sulfameter is a competitive inhibitor of the enzyme dihydropteroate synthase. This enzyme does the condensation of para-aminobenzoic acid (PABA) to produce folic acids. Without the synthesis of folate, the bacteria can not grow (bacteriostatic). Sulfameter is given orally as a tablet.
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Creator: Daphnee Created On: August 29, 2023 at 12:04 Last Updated: August 29, 2023 at 12:04 |
PW145821 |
drug action
Sulfameter Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 16:45 Last Updated: October 07, 2023 at 16:45 |
PW176137 |
Sulfameter Predicted Metabolism Pathway newHomo sapiens
Metabolites of Sulfameter are predicted with biotransformer.
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Creator: Omolola Created On: November 29, 2023 at 14:14 Last Updated: November 29, 2023 at 14:14 |
PW128425 |
drug action
Sulfamethazine Action PathwayEscherichia coli (strain K12)
Sulfamethazine is an antibacterial agent from the sulfanilamide drug class. It is used as a treatment for various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Sulfamethazine inhibits the dihydropteroate synthetase enzyme. This protein does the condensation of pteridine and para-aminobenzoic acid (PABA) to produce tetrahydrofolic acid (THF). THF is required for the synthesis of purine. The resulting inhibition causes the bacteria to be unable to grow (bacteriostatic). This drug is administered as an oral tablet.
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Creator: Daphnee Created On: August 28, 2023 at 13:40 Last Updated: August 28, 2023 at 13:40 |