PathWhiz

PathWhiz ID	Pathway	Meta Data
PW128400 View Pathway	drug action Sulfacetamide Action Pathway Escherichia coli (strain K12) Sulfacetamide is an anti-infective agent from the sulfonamide drug class (antibiotic). This drug can be used topically to treat skin infections (acne vulgaris), as well as orally to treat urinary tract infections. It is also indicated in the treatment of bacterial vaginitis, keratitis, acute conjunctivitis, and blepharitis. Sulfacetamide is a bacteriostatic drug, it stops the replication of the bacteria. This molecule binds to the dihydropteroate synthase protein in a wide-spectrum activity against most gram-positive and many gram-negative organisms. The inhibited enzyme is essential for the synthesis of folic acid from para-aminobenzoic acid (PABA) molecules. Folic acids are essential for the growth of the bacteria. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Daphnee Created On: August 28, 2023 at 10:06 Last Updated: August 28, 2023 at 10:06
PW132601 View Pathway	metabolic Sulfacetamide Drug Metabolism Homo sapiens Sulfacetamide is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Sulfacetamide passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 22:35 Last Updated: September 21, 2023 at 22:35
PW144748 View Pathway	drug action Sulfacetamide Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 14:20 Last Updated: October 07, 2023 at 14:20
PW128407 View Pathway	drug action Sulfacytine Action Pathway Escherichia coli (strain K12) Sulfacytine is a short-acting antibiotic from the sulfonamide drug class. This drug class consists of synthetic bacteriostatic antibiotics with a broad spectrum against most gram-positive and many gram-negative organisms. Sulfacytine is indicated in the treatment of acute urinary tract infections. Sulfacytine inhibits the multiplication of bacteria by acting as a competitive inhibitor of dihydropteroate synthase in the folic acid metabolism cycle. This enzyme does the condensation of the pteridine with the para-aminobenzoic acid (PABA). The inhibition causes the bacteria to stop growing. This drug is administered as an oral tablet but was discontinued in 2006 (FDA). BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Daphnee Created On: August 28, 2023 at 11:29 Last Updated: August 28, 2023 at 11:29
PW145365 View Pathway	drug action Sulfacytine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:40 Last Updated: October 07, 2023 at 15:40
PW144485 View Pathway	drug action Sulfadiazine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 13:43 Last Updated: October 07, 2023 at 13:43
PW176136 View Pathway	metabolic Sulfadiazine Predicted Metabolism Pathway new Homo sapiens Metabolites of Sulfadiazine are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: November 29, 2023 at 14:14 Last Updated: November 29, 2023 at 14:14
PW145662 View Pathway	drug action Sulfadimethoxine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:20 Last Updated: October 07, 2023 at 16:20
PW176356 View Pathway	metabolic Sulfadimethoxine Predicted Metabolism Pathway Homo sapiens Metabolites of sildenafil are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: December 07, 2023 at 15:29 Last Updated: December 07, 2023 at 15:29
PW145366 View Pathway	drug action Sulfadoxine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:40 Last Updated: October 07, 2023 at 15:40