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HMDB00058 HMDB DNA-binding transcriptional repressor 1.0 1.0 RNA polymerase, sigma 70 (sigma D) factor 1.0 DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerase subunit beta' DNA-directed RNA polymerase subunit beta' DNA-directed RNA polymerase subunit beta Reaction3679 false Activator-(CAP) binding site → Promoter LEFT_TO_RIGHT Reaction3678 false cAMP+CAP → Activator-(CAP) binding site + cAMP+CAP LEFT_TO_RIGHT 1.0 Reaction3677 false 2 Cyclic AMP + cAMP-activated global transcriptional regulator CRP → cAMP+CAP LEFT_TO_RIGHT cAMP-activated global transcriptional regulator CRP DNA-binding transcriptional repressor cAMP-activated global transcriptional regulator CRP RNA polymerase, sigma 70 (sigma D) factor 2.0 Cyclic AMP P0A8V2 UniProt DNA-directed RNA polymerase subunit alpha DNA-directed RNA polymerase subunit alpha Lac Operon Inactivation 2 C10H12N5O6P Cyclic AMP 329.05252 1.0 CHEBI:17489 ChEBI CAMP BioCyc operator 1.0 Beta-galactosidase Activator-(CAP) binding site Activator-(CAP) binding site Promoter operator Promoter C00575 KEGG Compound P0A7Z4 UniProt Beta-galactosidase PW000956 PathWhiz 2.0 P00579 UniProt 6076 PubChem-compound 5851 ChemSpider 1.0 P0ACJ8 UniProt SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O Reaction3682 false RNA polymerase sigma 70 → RNA polymerase sigma 70 + Promoter LEFT_TO_RIGHT Reaction3681 false operator → Beta-galactosidase LEFT_TO_RIGHT Reaction3680 false Promoter → operator LEFT_TO_RIGHT 1.0 60-92-4 CAS P0A8T7 UniProt SMP00972 SMPDB cAMP+CAP RNA polymerase sigma 70 cAMP-activated global transcriptional regulator CRP 2.0 Reaction3686 false DNA-binding transcriptional repressor → DNA-binding transcriptional repressor + operator LEFT_TO_RIGHT Mutant non-cAMP dependent cAMP receptor protein Mutant non-cAMP dependent cAMP receptor protein Mutant non-cAMP dependent cAMP receptor protein DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerase subunit alpha DNA-directed RNA polymerase subunit beta' RNA polymerase sigma factor FliA DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerase subunit alpha DNA-directed RNA polymerase subunit beta' RNA polymerase sigma factor FliA DNA-binding transcriptional repressor DNA-binding transcriptional repressor Cyclic AMP D-Glucose Alpha-Lactose Cyclic AMP Cyclic AMP Activator-(CAP) binding site Activator-(CAP) binding site Promoter operator lacZ Promoter operator lacY lacA No Glucose No Lactose No Transcription
HMDB00058 HMDB DNA-binding transcriptional repressor 1.0 1.0 RNA polymerase, sigma 70 (sigma D) factor 1.0 DNA-directed RNA polymerase subunit beta DNA-directed RNA polymerase subunit beta' DNA-directed RNA polymerase subunit beta' DNA-directed RNA polymerase subunit beta Reaction3679 false Activator-(CAP) binding site → Promoter LEFT_TO_RIGHT Reaction3678 false cAMP+CAP → Activator-(CAP) binding site + cAMP+CAP LEFT_TO_RIGHT 1.0 Reaction3677 false 2 Cyclic AMP + cAMP-activated global transcriptional regulator CRP → cAMP+CAP LEFT_TO_RIGHT cAMP-activated global transcriptional regulator CRP DNA-binding transcriptional repressor cAMP-activated global transcriptional regulator CRP RNA polymerase, sigma 70 (sigma D) factor 2.0 Cyclic AMP P0A8V2 UniProt DNA-directed RNA polymerase subunit alpha DNA-directed RNA polymerase subunit alpha Lac Operon Inactivation 2 C10H12N5O6P Cyclic AMP 329.05252 1.0 CHEBI:17489 ChEBI CAMP BioCyc operator 1.0 Beta-galactosidase Activator-(CAP) binding site Activator-(CAP) binding site Promoter operator Promoter C00575 KEGG Compound P0A7Z4 UniProt Beta-galactosidase PW000956 PathWhiz 2.0 P00579 UniProt 6076 PubChem-compound 5851 ChemSpider 1.0 P0ACJ8 UniProt SMILES NC1=NC=NC2=C1N=CN2[C@@H]1O[C@@H]2COP(O)(=O)O[C@H]2[C@H]1O Reaction3682 false RNA polymerase sigma 70 → RNA polymerase sigma 70 + Promoter LEFT_TO_RIGHT Reaction3681 false operator → Beta-galactosidase LEFT_TO_RIGHT Reaction3680 false Promoter → operator LEFT_TO_RIGHT 1.0 60-92-4 CAS P0A8T7 UniProt http://identifiers.org/smpdb/SMP00972 SMPDB cAMP+CAP RNA polymerase sigma 70 cAMP-activated global transcriptional regulator CRP 2.0 Reaction3686 false DNA-binding transcriptional repressor → DNA-binding transcriptional repressor + operator LEFT_TO_RIGHT crp(in) crp(in) crp(in) rpoB rpoA rpoC fliA rpoB rpoA rpoC fliA lacI lacI Cyclic AMP D-Glucose Alpha-Lactose Activator- (CAP) binding site Activator- (CAP) binding site Promoter operator Beta- galactosidase Promoter operator Lactose permease Galactoside O- acetyltransferase